Most military aircrew undergo hypoxia training, including experience in decompression chamber, to understand the ill-effects of the silent but deadly hazard of in-flight hypoxia [1]. Symptoms experienced during the classic mask-off hypoxia indoctrination in altitude/decompression chamber correlates well with reported in-flight symptoms [2]. The objectives of hypoxia indoctrination, an effects-based training, is to make aircrew …